HCM
HCM AFIB ANTICOAGULATION
-In regards to anticoagulation, Under normal circumstances, we would
utilize the CHADS2-VASc scoring system for risk of thromboembolic
events. However, in those studies, HCM patients were not included (in
most of those studies) and thus is not be clinically applicable
-There have been several studies linking the increased risk of
Afib and CVA with HCM (Olivotto I et al. "Impact of atrial
fibrillation on the clinical course of hypertrophic
cardiomyopathy." Circulation. 2001;104(21):2517.)
-This is reflected in the 2014 AHA / ACC Afib guidelines in that
the anticoagulation should be given for HCM patients
independent of CHADS2-VASc score (Class I indication)
HCM - AFIB AAD
-In regards to AAD, the 2014 AHA / ACC AFib guidelines give Amiodarone
or Disopyramide (in conjuncture with an AVN Blocking Agent) to prevent
recurrent afib in patients with HCM (January, Craig et al. "2014 AHA /
ACC / HRS Guideline for the management of patients with atrial
fibrillation." Circulation. 2014;130:e199-e267)